VIM Mouse anti-Human, Clone: LN-6, Abnova™
Mouse monoclonal antibody raised against native human VIM.
Manufacturer: Abnova Corporation MAB13451
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
|Mouse monoclonal antibody raised against native human VIM.|
|In 10mM PBS (0.05% BSA, 0.05% sodium azide).|
|Store at 4°C.|
|This monoclonal antibody reacts with a non-hematopoietic epitope of VIM and shows no cross-reaction with other closely related intermediate filament proteins such as desmin, keratin, neurofilament, and glial fibrillary acid protein.|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)|
|Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.|
|Human thymic nuclear extract.|
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