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Vimentin Mouse anti-Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat, Alexa Fluor™ 532, Clone: VM452, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233060AF532

Catalog No. NP233060A32


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Description

Description

Vimentin Monoclonal antibody specifically detects Vimentin in Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse, Rat samples. It is validated for Western Blot, ELISA.
Specifications

Specifications

Vimentin
VM452
Western Blot, ELISA
Conjugated, Purified
VIM
A recominant protein fragment specific to Vimentin was used as the immunogen for the VM452 antibody.
Protein G purified
Biologically Active Proteins, Cancer, Cellular Markers, Cytoskeleton Markers, Growth and Development, Hypoxia, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Phospho Specific, Signal Transduction, Stem Cell Markers, Stem Cells
Primary
7431.0
Bovine, Canine, Chicken, Feline, Goat, Human, Mouse, Porcine, Rat
ELISA, Western Blot
Alexa Fluor™ 532
50 mM sodium borate with 0.05% sodium azide
FLJ36605, vimentin
Mouse
IgG1
0.1 mL
Store at 4°C in the dark.
Monoclonal
This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP′s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein. Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
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