Epredia™ Lab Vision™ Vinculin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ Vinculin Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1209R1

Catalog No. MS1209R1

Description

Vinculin is an attachment protein involved in the indirect binding of intracellular actin filaments to extracellular fibronectin. Vinculin binds to actin capping protein and α actinin, which in turn binds to actin. The binding of fibronectin is also indirect where vinculin binds to talin, which in turn binds to the intracellular domain of the fibronectin receptor which itself is the ligand for fibronectin. Vinculin is widely distributed in tissue and is expressed where smooth muscle actin and fibroblasts attach to the extracellular matrix.

Host Species: Mouse

Clone: VLN01

Isotype: IgG

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Semi-purified vinculin

Molecular Weight: 130kDa (vinculin) and 150kDa (meta-vinculin)

Positive Control: HeLa cells, skin

Cellular Localization: Cell membrane and cytoplasmic Ab-1 is useful for studies of vinculin in platelet activation.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Vinculin Ab-1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Cytoskeletal Protein
• Target Species: Human
• Isotype: IgG

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: VLN01
• Formulation: Ready-to-use for IHC (UVLP)
• Immunogen: Semi-purified vinculin
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Prediluted