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Vinculin Mouse anti-Human, Mouse, Rat, Clone: 7F9, eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  LIFE TECHNOLOGIES 14977795

Encompass

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Catalog No. 14-977-795


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Description

Description

The MAb 7F9 (VIIF9) recognizes human, mouse, rat, and avian vinculin and its alternatively spliced isoform, metavinculin. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin is involved in the anchoring of F-actin to the membrane and the regulation of E-cadherin expression. Vinculin binds to talin, paxillin, and alpha-actinin. Disregulation of vinculin alters cell adhesion, migration, and growth, which promotes cancer invasion and metastasis.

Vinculin Monoclonal antibody specifically detects Vinculin in Human, Mouse, Rat samples. It is validated for Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Specifications

Specifications

Vinculin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P18206, P85972, Q64727
Mouse
10 mg
Primary
Human, Mouse, Rat
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
7F9
Unconjugated
VCL
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; Metavinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; VCL; vcl {ECO:0000250; VIN; vinc; VINC1; Vinculin; vinculin {ECO:0000250
Affinity chromatography
RUO
22330, 305679, 7414
Antibody
IgG1 κ
Safety and Handling

Safety and Handling

SDS
Documents
Product Certifications
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