Orally active alpha-glucosidase inhibitor
Manufacturer: Tocris 3596/50
DescriptionOrally active α-glucosidase inhibitor (IC50 values are 3.9 and 6.4nM at sucrase and maltase respectively). Increases glucagon-like peptide 1 (GLP-1) secretion and decreases food consumption in ob/ob mice, and reduces plasma concentrations of glucose, triglycerides and insulin in Wistar fatty rats. Exhibits antidiabetic and antiobesity activity in vivo.
- Chemical Name: 3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol
- Formula: C10H21NO7
- CAS Number: 83480-29-9
- Solubility: Soluble to 100mM in water and to 75mM in DMSO
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