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Thermo Scientific™ Lab Vision™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen von Hippel-Lindau (vHL) Protein Ab-1
Clone Ig33
Classification Monoclonal
Format Concentrated
Host Species Murine
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Products 3
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS690P1
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Thermo Scientific™
MS690P1
200μg/mL Unconjugated 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS690P1ABX
View Documents
Thermo Scientific™
MS690P1ABX
1mg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS690P0
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Thermo Scientific™
MS690P0
200μg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.

Molecular genetic studies suggest that VHL is a tumor-suppressor gene. Alterations in the von Hippel-Lindau (VHL) gene are correlated with a diverse group of neoplasms including hemangioblastoma, clear cell renal carcinoma (RCC), and pheochromocytoma. Two transcriptional elongation factors, Elongin B and C, are shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. It is proposed that pVHL functions in vivo as a negative regulator of transcription elongation.

Host Species: Mouse

Clone: Ig33

Isotype: IgG1/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 1-54

Immunogen: A recombinant protein containing aa 1-213 of human vHL

Molecular Weight: 30kDa

Positive Control: Kidney

Cellular Localization: Cytoplasmic Ab-1 does not recognize the truncated form of VHL protein.

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

von Hippel-Lindau (vHL) Protein Ab-1
Monoclonal
Murine
Cancer and Tumor Biology
A recombinant protein containing aa 1-213 of human VHL
Ig33
Concentrated
RUO
Primary
IgG2a kappa
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