Invitrogen™ Human VWF Native Protein

Description

Native Protein

RP-43132 contains native human von Willebrand Factor protein. RP-43132 may be used as a positive control in many immunological assays. The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis.

Specifications

• Accession Number: P04275
• Concentration: 0.17 mg/mL
• For Use With (Application): Control
• Formulation: 0.025 M citric acid with 0.1 M glycine, 0.1 M NaCl and no preservative; pH 6.8
• Gene ID (Entrez): 7450
• Molecular Weight (g/mol): 260 kDa
• Name: Human VWF
• pH Range: 6.8
• Quantity: 100 μg
• Source: Human
• Regulatory Status: RUO
• Gene Alias: 6820430P06Rik; AI551257; B130011O06Rik; C630030D09; Coagulation Factor VIII; coagulation factor VIII VWF; EMBL:CAB37852.1}; F8VWF; factor viii related antigen; von Willebrand antigen 2; von Willebrand antigen II; von Willebrand Disease (vWD); von Willebrand factor; Von Willebrand factor homolog; VWD; vwf; vwf {ECO:0000312
• Common Name: VWF
• Gene Symbol: VWF
• Conjugate: Unconjugated
• Species: Human
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Protein Subtype: Native