VPS8 Mouse anti-Human, Clone: 2C8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524456
Peptide Sequence: RITPSQVKMS PSYHQSKGDP TAKKGTSEPV LDPQQIQAFD QLCRLYRGSS RLALLTELSQ NRSSESYRPF SGSQSAPAFN SIFQNENFQL QLIPPPVTEDPlays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predomitly in APPL1-containing endosomes (PubMed:25266290).
|KIAA0804 (NP_001009921, 1329 a.a. ∽ 1428 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
|ELISA, Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with no preservative; pH 7.4|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok