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VPS8 Mouse anti-Human, Clone: 2C8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524456

Catalog No. PIMA524456


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Description

Description

Peptide Sequence: RITPSQVKMS PSYHQSKGDP TAKKGTSEPV LDPQQIQAFD QLCRLYRGSS RLALLTELSQ NRSSESYRPF SGSQSAPAFN SIFQNENFQL QLIPPPVTED

Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predomitly in APPL1-containing endosomes (PubMed:25266290).
Specifications

Specifications

VPS8
Monoclonal
Unconjugated
VPS8
Liquid
VPS8
KIAA0804 (NP_001009921, 1329 a.a. ∽ 1428 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
2C8
PBS with no preservative; pH 7.4
Q8N3P4
VPS8; KIAA0804
Mouse
IgG2b, kappa
100 μg
-20° C
Primary
23355
Documents
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