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VRK1 Mouse anti-Human, Clone: OTI2E10, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF805791

Catalog No. 50-166-7567


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
Specifications

Specifications

VRK1
Monoclonal
Unconjugated
VRK1
Lyophilized
VRK1
Human recombit protein fragment corresponding to amino acids 1-230 of human VRK1 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
OTI2E10
PBS with 8% trehalose and no preservative; pH 7.3
Q99986
PCH1, PCH1A
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7443
SDS
Documents
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