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Tocris™ VU 0255035

Highly selective muscarinic M1 antagonist

Manufacturer:  Tocris™ 3727/10

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Catalog No. 37-271-0R

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For Research Use Only



Highly selective muscarinic M1 antagonist (Ki = 14.87nM). Targets the M1 orthosteric site with greater than 75-fold selectivity over the other receptor subtypes. Reduces pilocarpine-induced seizures in mice. Brain penetrant.
  • Chemical Name: N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
  • Formula: C18H20N6O3S2
  • CAS Number: 1135243-19-4
  • Solubility: Soluble to 20mM in DMSO
  • Purity: >99
Description & Specifications


VU 0255035
VU 0255035
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