Tocris™ VU 0255035

Highly selective muscarinic M1 antagonist

Manufacturer: Tocris™ 3727/50

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Catalog No. 37-275-0R

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For Research Use Only


    Product Type VU 0255035
    Inhibitors VU 0255035
    Purity >99
    Molecular Weight 432.52
    Quantity 50mg

    Highly selective muscarinic M1 antagonist (Ki = 14.87nM). Targets the M1 orthosteric site with greater than 75-fold selectivity over the other receptor subtypes. Reduces pilocarpine-induced seizures in mice. Brain penetrant.

    • Chemical Name: N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
    • Formula: C18H20N6O3S2
    • CAS Number: 1135243-19-4
    • Solubility: Soluble to 20mM in DMSO
    • Purity: >99

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