Tocris™ VU 0361737

Selective positive allosteric modulator at mGlu4

Manufacturer: Tocris™ 3707/50

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Catalog No. 37-075-0R

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For Research Use Only


    Inhibitors VU 0361737
    Purity >99
    Molecular Weight 262.69
    Quantity 50mg
    Product Type VU 0361737

    Selective positive allosteric modulator at mGlu4 receptors (EC50 values are 240 and 110nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors and displays weak activity at mGlu5 and mGlu8 receptors. Brain penetrant.

    • Chemical Name: N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
    • Formula: C13H11ClN2O2
    • CAS Number: 1161205-04-4
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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