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Tocris Bioscience™ VU 0409106

Potent and selective negative allosteric modulator at mGlu5

$164.80 - $693.50


Chemical Name or Material 3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide
Molecular Formula C15H11FN4O2S
CAS 1276617-62-9
Product Type Target: Group I mGluR Modulators
Formula Weight 330.34
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53-221-0 View Documents Tocris Bioscience™
10mg Each for $164.80
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53-225-0 View Documents Tocris Bioscience™
50mg Each for $693.50
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Potent and selective mGlu5 negative allosteric modulator (IC50 = 49 nM at human mGlu5). Selective for mGlu5 over a panel of GPCRs and ion channels. Exhibits no significant nonspecific binding in rat brain homogenates in vitro. Inhibits marble burying behavior in mice. Brain penetrant.


Target: Group I mGluR Modulators
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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