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Tocris Bioscience™ VU 0409551 Available on GSA/VA Contract for Federal Government customers only.

Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable

$198.00 - $832.00

Specifications

Chemical Name or Material [6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
Molecular Formula C20H17FN2O3
CAS 1363281-27-9
Product Type Target: Group I mGluR Modulators
Formula Weight 352.36
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
56-935-0 View Documents Tocris Bioscience™
5693/50
50mg Each for $832.00
Add to cart
 
56-931-0 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5693/10
10mg Each for $198.00
Add to cart
 
Description

Description

Selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via Gαq. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available.

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Specifications

Specifications

[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](fluorophenyl)methanone
1363281-27-9
352.36
C20H17FN2O3
Target: Group I mGluR Modulators
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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