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VWF Monoclonal Antibody (OTI9C12), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA803499

Encompass_Preferred

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Catalog No. 50-167-9786


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Description

Description

Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein, which binds to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. It is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/ store) this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or maligt. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.
Specifications

Specifications

VWF
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P04275
VWF
Human recombit protein fragment corresponding to amino acids 764-1263 of human VWF produced in SF9 cell.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI9C12
Unconjugated
VWF
F8VWF, VWD
Mouse
Affinity Chromatography
RUO
7450
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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