WASL Mouse anti-Human, Mouse, Clone: OTI9F2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811284

Catalog No. 50-167-0574

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. The WASL gene product is a homolog of WAS protein, however, unlike the latter, it is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

Specifications

• Antigen: WASL
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: WASL
• Gene Alias: N-WASP, NWASP, WASPB
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 73178, 8976
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI9F2
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O00401, Q91YD9
• Gene Symbols: WASL
• Immunogen: Full length human recombit protein of human WASL produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b