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WDR77 Mouse anti-Human, Mouse, Rat, Clone:8A10-C10-E8, Abnova™

Mouse monoclonal antibody raised against recombinant human WDR77.

Manufacturer:  Abnova Corporation MAB17667

Catalog No. 89-333-875


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Description

Description

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM]
Specifications

Specifications

WDR77
8A10-C10-E8
WD repeat domain 77
In PBS, pH 7.4 (50% glycerol, 0.02% sodium azide)
Liquid
Mouse
IgG1
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
This antibody detects endogenous levels of WDR77 and does not cross-react with related proteins.
Immunocytochemistry, Western Blot
Unconjugated
Immunocytochemistry (1:100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
WDR77
HKMT1069, MEP50, MGC2722, Nbla10071, RP11-552M11.3, p44
Recombinant protein corresponding to a fragment of human WDR77 from E. coli.
100μg
Antibody
79084
Human, Mouse, Rat
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