WDR77 Mouse anti-Human, Mouse, Rat, Clone:8A10-C10-E8, Abnova
Mouse monoclonal antibody raised against recombinant human WDR77.
Manufacturer: Abnova Corporation MAB17667
DescriptionWDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM]
|WD repeat domain 77|
|In PBS, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody detects endogenous levels of WDR77 and does not cross-react with related proteins.|
|Immunocytochemistry, Western Blot|
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
|HKMT1069, MEP50, MGC2722, Nbla10071, RP11-552M11.3, p44|
|Recombinant protein corresponding to a fragment of human WDR77 from E. coli.|
|Human, Mouse, Rat|