Invitrogen™ WFDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544792

Catalog No. PIPA544792

Description

Peptide sequence: WKRALPARLA EKSRAEEAGA PGGPRQPRAD RCPPPPRTLP PGACQAARCQ Sequence homology: Dog: 91%; Human: 100%.

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Specifications

• Antigen: WFDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WFDC1
• Gene Alias: 2310058A03Rik; Prostate stromal protein ps20; PS20; ps20 growth inhibitor; WAP four-disulfide core domain 1; WAP four-disulfide core domain 1 homolog; WAP four-disulfide core domain protein 1; Wfdc1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58189
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9HC57
• Gene Symbols: WFDC1
• Immunogen: Synthetic peptide directed towards the N-terminal of human WFDC1 (aa 35-84).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov