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WIBG Mouse anti-Human, Clone: OTI9C7, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF806506

Catalog No. 50-166-7864


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo.
Specifications

Specifications

WIBG
Monoclonal
Unconjugated
PYM1
Lyophilized
PYM1
Full length human recombit protein of human WIBG produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin)
OTI9C7
PBS with 8% trehalose and no preservative; pH 7.3
Q9BRP8
PYM, WIBG
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
84305
SDS
Documents
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