WIPI1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA585563

Catalog No. PIPA585563

Description

Keep as concentrated solution. Predicted reactivity: Mouse (94%), Rat (94%), Pig (96%), Bovine (90%). Positive Control: HepG2, human WIPI1-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

WIPI1 (WD repeat domain, phosphoinositide interacting-1), also known as WIPI1, ATG18 or WIPI49, is thought to play a role in autophagy and may regulate protein trafficking in certain recycling pathways. It contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. WIPI1 localizes to cytoplasmic vesicles, endosomes, clathrin-coated vesicles and the trans-Golgi network. It is ubiquitously expressed with highest expression in heart, testis, placenta, pancreas and skeletal muscle. WIPI1 is upregulated in a variety of tumors, suggesting a role in carcinogenesis.

Specifications

• Antigen: WIPI1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WIPI1
• Gene Alias: 4930533H01Rik, ATG18, Atg18 protein homolog, ATG18A, AW411817, D11Ertd498e, RGD1307754, WD repeat domain phosphoinositide-interacting protein 1, WD repeat domain, phosphoinositide interacting 1, WD40 repeat protein interacting with phosphoinositides of 49 kDa, WD40 repeat protein Interacting with phosphoInositides of 49kDa, WIPI 49 kDa, Wipi1, WIPI-1, WIPI-1 alpha, WIPI49
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55062
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
• Gene Accession No.: Q5MNZ9
• Gene Symbols: WIPI1
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human WIPI1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov