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WIT1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 154581AP

Catalog No. 50-173-0244


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Description

Description

The Wilms Tumor 1 gene encodes one of the WPP domain-interacting proteins (Wilms Tumor 1/AT5G11390, WIT2/AT1G68910) required for RanGAP nuclear envelope association in root tip cells. Ran GTPase plays essential roles in multiple cellular processes, including nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. The cytoplasmic Ran GTPase activating protein RanGAP is critical to establish a functional RanGTP/RanGDP gradient across the nuclear envelope and is associated with the outer surface of the nuclear envelope in metazoan and higher plant cells. Arabidopsis thaliana RanGAP association with the root tip nuclear envelope requires a family of likely plant-specific nucleoporins combining coiled-coil and transmembrane domains (CC-TMD) and WPP domain-interacting proteins (WIPs). Wilms Tumor 1 and WIT2 have been identified as a second family of CC-TMD proteins, structurally similar, yet clearly distinct from the WIP family, that is required for RanGAP nuclear envelop association in root tip cells.
Specifications

Specifications

WIT1
0.37 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q06250
WIT 1, WIT1
Rabbit
IgG
150 μL
-20°C
Primary
51352
Immunohistochemistry (Paraffin)
Unconjugated
WT1-AS
Liquid
WT1-AS
WIT1 Fusion Protein Ag7728
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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