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WRN Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 252691AP

Catalog No. 50-173-4825


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Description

Description

This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predomit nucleolar localization. It possesses an intrinsic 3 ft. to 5 ft. DNA helicase activity, and is also a 3 ft. to 5 ft. exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
Specifications

Specifications

WRN
0.56 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q14191
DNA helicase, RecQ like type 3, Exonuclease WRN, RecQ protein like 2, RECQ3, RECQL2, RECQL3, WRN
Rabbit
IgG
150 μL
-20°C
Primary
7486
Western Blot
Unconjugated
WRN
Liquid
WRN
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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