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WWOX Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 152991AP

Catalog No. 50-173-0132


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Description

Description

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
Specifications

Specifications

WWOX
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q91WL8, Q9NZC7
D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1, WWOX
Rabbit
IgG
150 μL
-20°C
Primary
292041, 51741, 80707
Immunoprecipitation, Western Blot
Unconjugated
WWOX
Liquid
WWOX
WWOX Fusion Protein Ag7555
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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