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WWTR1 Mouse anti-Human, Clone: CL0371, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524604

Catalog No. PIMA524604


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Description

Description

Immunogen sequence: MNPKPSSWRK KILPESFFKE PDSGSHSRQS STDSSGGHPG PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP LPPGWEMTFT ATGQRYFLNH IEKITTWQDP RKAMNQPLNH MNLHPAVSST Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%. Binds to an epitope located within the peptide sequence SSWRKKILPESFFKE as determined by overlapping synthetic peptides.

Highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. A novel transcriptional co-activator, TAZ (transcriptional co-activator with PDZ-binding motif) functions as a 14-3-3-binding molecule. TAZ may link events at the plasma membrane and cytoskeleton to nuclear transcription in a manner that can be regulated by 14-3-3.
Specifications

Specifications

WWTR1
Monoclonal
1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9GZV5
DKFZp586I1419, FLJ27004, FLJ45718, TAZ
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
25937
Immunohistochemistry, Western Blot
CL0371
Unconjugated
WWTR1
Liquid
WWTR1
Recombit protein corresponding to Human WWTR1
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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