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Tocris™ WZ 4003

Potent and selective NUAK1/2 inhibitor

Manufacturer:  Tocris™ 5177/50

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Catalog No. 51-775-0

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For Research Use Only



Potent and selective NUAK1/2 inhibitor (IC50 values are 20 and 100nM respectively). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells.
  • Chemical Name: N-3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide
  • Formula: C25H29ClN6O3
  • CAS Number: 1214265-58-3
  • Solubility: Soluble to 50mM in 1eq. HCl and to 20mM in DMSO with gentle warming
  • Purity: >98
Description & Specifications


WZ 4003
WZ 4003
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