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Tocris Bioscience™ Xanomeline oxalate

Functionally selective M1 agonist

Supplier:  Tocris Bioscience™ 3569/50

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Catalog No. 35-695-0R


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Description

Description

Xanomeline oxalate is a functionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4. Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
Specifications

Specifications

>98%
Xanomeline oxalate
Xanomeline oxalate
50 mg
371.46
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