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Tocris™ Xanomeline oxalate

Functionally selective M1 agonist

Manufacturer:  Tocris™ 3569/10

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Catalog No. 35-691-0R


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Disclaimers:

For Research Use Only


Specifications

Description

Functionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5nM at M1, M3, M5, M4 and M2 receptors respectively). Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4. Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
  • Chemical Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate
  • Formula: C19H20BrN3O3
  • CAS Number: 84379-13-5
  • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
  • Purity: >98
Description & Specifications

Specifications

Xanomeline oxalate
>98
10mg
Xanomeline oxalate
371.46
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