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XCR1/CCXCR1 Rabbit anti-Human, PE, Clone: 1097A, R&D Systems™

Recombinant Monoclonal Antibody

Manufacturer:  R&D Systems FAB8571P025

Catalog No. FAB8571P025


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Description

Description

XCR1, also known as GPR5 and Lymphotactin/SCM-1 (Single Cysteine Motif 1) Receptor, is a 38kDa member of the G-protein coupled receptor 1 family. It binds XCL1/Lymphotactin/SCM-1α and XCL2/SCM-1β. In addition, Human Herpes Virus 8 (HHV8) encodes two viral chemokines vCCL2/vMIP-II and vCCL3/vMIP-III that function as an antagonist and a highly selective agonist, respectively, for XCR1. XCR1 is expressed on neutrophils, CD8+ T cells, NK cells, CD4+ T cells and B cells. Human XCR1 is a 333 amino acid (aa), 7-transmembrane molecule. It contains a 32 aa N-terminus that lacks glycosylation sites and a 42 aa C-terminal cytoplasmic tail. Over the extracellular regions used for immunization, human XCR1 shares 62%, 54% and 64% aa identity with canine, mouse and porcine XCR1, respectively.
Specifications

Specifications

XCR1/CCXCR1
1097A
Flow Cytometry 10 uL/10^6 cells
P46094
CCXCR1, CCXCR1XC chemokine receptor 1, chemokine (C motif) receptor 1, chemokine XC receptor 1, G protein-coupled receptor 5, GPR5, GPR5chemokine (C motif) XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor
Rabbit
IgG
25 Tests
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Monoclonal
Detects human XCR1 in direct ELISAs.
Flow Cytometry
R-PE
Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
Purified
XCR1
E. coli-derived recombinant human XCR1 Met1-Thr31, Ser89-Lys103, His168-His190, Phe251-Tyr267 Accession # P46094
Protein A or G purified from cell culture supernatant
RUO
Primary
2829
Human
SDS
Documents
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