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XE 991 dihydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Potent and selective blocker of KV7 (KCNQ) voltage-gated potassium channels. Blocks KV7.2+7.3 (KCNQ2+3)/ M-currents (IC50 = 0.6 - 0.98 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 0.75 μM) but is less potent against KV7.1/minK channels (IC50 = 11.1 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo.
Specifications
Quantity | 50 mg |
Formula Weight | 449.37 |
Percent Purity | >99% |
Chemical Name or Material | XE 991 dihydrochloride |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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