Tocris Bioscience XL 388
Potent and selective mTOR inhibitor; antitumor
Manufacturer: Tocris Bioscience 4893/10
DescriptionPotent and selective mTOR inhibitor (IC50 = 9.9 nM). Inhibits mTOR activity in an ATP-competitive manner. Exhibits >300-fold selectivity for mTOR over PI 3-K and a range of other kinases. Displays antitumor activity in athymic nude mice implanted with tumor xenografts.
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