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Thermo Scientific™ Lab Vision™ XPA Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ XPA Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen XPA Ab-1
Clone 12F5
Applications Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS650R1
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Thermo Scientific™
MS650R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS650P0
View Documents
Thermo Scientific™
MS650P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ XPA Ab-1, Mouse Monoclonal Antibody.

The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV-or chemically damaged DNA lesions, and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or the excision repair cross complementing 1 protein (ERCC1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a > 2000 fold increased risk to develop skin cancer at sun-exposed areas.

Host Species: Mouse

Clone: 12F5

Isotype: IgG2a/k

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPA protein

Molecular Weight: ~40kDa

Positive Control: Ls174T or MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

XPA Ab-1
Western Blot
Unconjugated
RUO
Primary
IgG2a kappa
12F5
Monoclonal
Murine
DNA Repair
Recombinant human XPA protein
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