XPC Mouse anti-Human, Clone: 3.26, Abnova™
Mouse monoclonal antibody raised against human XPC.
Manufacturer: Abnova Corporation MAB12528
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
|Mouse monoclonal antibody raised against human XPC.|
|In PBS, pH 7.2.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Immunofluorescence Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human XPC.|
|Protein G purification|
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