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Thermo Scientific™ Lab Vision™ XPF Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen XPF Ab-1
Clone 219
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS1381R1
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Thermo Scientific™
MS1381R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1381P0
View Documents
Thermo Scientific™
MS1381P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ XPF Ab-1, Mouse Monoclonal Antibody.

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV-induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross-links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision.

Host Species: Mouse

Clone: 219

Isotype: IgG2/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human XPF protein

Molecular Weight: ~110kDa

Positive Control: MCF-7 cells or human tonsil

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

XPF Ab-1
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
RUO
Primary
IgG2
219
Monoclonal
Murine
DNA Repair
Recombinant human XPF protein
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