XPF Mouse anti-Human, Mouse, Clone: OTI4E11, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA503261
DescriptionThe structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3 ft. of the DNA lesion while the ERCC1 / XPF complex makes the 5 ft. incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|ERCC11, FANCQ, RAD1, XFEPS, XPF|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of human ERCC4 produced in HEK293 cell.|
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