XPO4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141633

Catalog No. 01-675-246

Description

PA1-41633 detects Exportin-4 in chicken, chimpanzee, rhesus monkey, canine, human, rat and mouse samples. This antibody is predicted to react with bovine, xenopus, and zebrafish based on sequence homology. Suggested positive control: Jurkat whole cell lysate.

Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.

Specifications

• Antigen: XPO4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: XPO4
• Gene Alias: B430309A01Rik; exp4; exportin 4; exportin-4; FLJ13046; hypothetical protein; KIAA1721; mKIAA1721; RCJMB04_1f17; Xpo4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 290280, 428081, 477344, 57258, 64328
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.2% gelatin and 0.05% sodium azide
• Gene Accession No.: Q5ZMR9, Q9C0E2, Q9ESJ0
• Gene Symbols: XPO4
• Immunogen: Synthetic peptide corresponding to residues 850-950 of human Exportin-4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Chicken, Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG