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Epredia™ Lab Vision™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Provide accurate, reproducible results with the Epredia™ XRCC1 (X-Ray Repair Cross Complementing Protein 1) Ab-3, Mouse Monoclonal Antibody.
Supplier: Epredia™ MS1393R1
Description
X-Ray Repair Cross Complementing (XRCC1) plays a role in excision repair of DNA after ionizing irradiation. XRCC1 binds to DNA ligase III through the C-terminal 96 amino acids and to DNA polymerase β through the N-terminal half. In testis XRCC1 is expressed at high levels. Cells with a mutation of this gene exhibit decreased single strand break repair and reduced recombination repair. They show increased double strand breaks, and sister chromatid exchange is increased up to 10-fold. The XRCC1 might serve as a scaffold protein during base excision-repair.Host Species: Mouse
Clone: 144
Isotype: IgG2a/κ
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Recombinant human XRCC1 protein
Molecular Weight: 85kDa
Positive Control: Ls174T, or HeLa cells; normal testis
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
XRCC1 (X-Ray Repair Cross Complementing Protein1) Ab-3 | |
Monoclonal | |
Unconjugated | |
Mouse | |
1 mL | |
DNA Repair | |
Human | |
IgG2a κ |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
144 | |
Ready-to-use for IHC (UVLP) | |
Recombinant human XRCC1 protein | |
RUO | |
Primary | |
Ready-to-Use |
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