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XRCC4 Rabbit anti-Human, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 158171AP

Catalog No. 50-173-0504


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Description

Description

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.
Specifications

Specifications

XRCC4
0.28 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13426
DNA repair protein XRCC4, XRCC4
Rabbit
IgG
150 μL
-20°C
Primary
309995, 7518
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
XRCC4
Liquid
Xrcc4
XRCC4 Fusion Protein Ag8606
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat
Documents
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