XRCC5 Mouse anti-Human, Clone: 9403, Abnova™
Mouse monoclonal antibody raised against partial recombinant human XRCC5.
Manufacturer: Abnova Corporation MAB12933
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
|Mouse monoclonal antibody raised against partial recombinant human XRCC5.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to N-terminus of human XRCC5.|
|Protein G purification|
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