XTP4 Mouse anti-Human, Clone: OTI4D4, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526354
DescriptionDuring the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3 ft. end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|C35, MGC14832, ORB3, RDX12, XTP4|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of C17orf37 produced in E.coli|
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