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YM 298198 hydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1216398-09-2
C18H23ClN4OS
378.919
WYTJVUVCSUWZTH-UHFFFAOYSA-N
ym 298198 hydrochloride,6-amino-n-cyclohexyl-n,3-dimethylthiazolo 3,2-a benzimidazole-2-carboxamide hydrochloride,ym-298198 hydrochloride hplc,thiazolo 3,2-a benzimidazole-2-carboxamide,6-amino-n-cyclohexyl-n,3-dimethyl,11-amino-n-cyclohexyl-n,3-dimethyl-5-thia-2,7-diazatricyclo 6.4.0.0_,? dodeca-1 12 ,3,6,8,10-pentaene-4-carboxamide hydrochloride,6-amino-n-cyclohexyl-n,3-dimethyl 1,3 thiazolo 3,2-a benzimidazole-2-carboxamide-hydrogen chloride 1/1
45073464
7-amino-N-cyclohexyl-N,1-dimethyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride
CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4.Cl
This item is not returnable. View return policy
1216398-09-2
C18H23ClN4OS
378.919
WYTJVUVCSUWZTH-UHFFFAOYSA-N
ym 298198 hydrochloride,6-amino-n-cyclohexyl-n,3-dimethylthiazolo 3,2-a benzimidazole-2-carboxamide hydrochloride,ym-298198 hydrochloride hplc,thiazolo 3,2-a benzimidazole-2-carboxamide,6-amino-n-cyclohexyl-n,3-dimethyl,11-amino-n-cyclohexyl-n,3-dimethyl-5-thia-2,7-diazatricyclo 6.4.0.0_,? dodeca-1 12 ,3,6,8,10-pentaene-4-carboxamide hydrochloride,6-amino-n-cyclohexyl-n,3-dimethyl 1,3 thiazolo 3,2-a benzimidazole-2-carboxamide-hydrogen chloride 1/1
45073464
7-amino-N-cyclohexyl-N,1-dimethyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride
CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4.Cl

Highly potent, selective non-competitive mGlu1 antagonist

Non-competitive antagonist with high affinity and selectivity for mGlu 1 receptors (K i = 19 nM); inactive at other mGlu receptor subtypes (mGlu 2-7 ), ionotropic receptors and glutamate transporters (IC 50 > 10 μM). Inhibits glutamate-induced IP production more potently than CPCCOEt (IC 50 values are 16 nM and 6.3 μM respectively), and is orally active in vivo, demonstrating an antinociceptive effect in hyperalgesic mice. Desmethyl Derivative also available.

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Quantity 10mg
Formula Weight 378.92
Percent Purity >99%
Chemical Name or Material YM 298198 hydrochloride

Recommended Storage : Desiccate at +4°C