Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

YM 298198 hydrochloride, Tocris Bioscience™

Click to view available options
Quantity:
10mg
50mg
This item is not returnable. View return policy
1216398-09-2
C18H23ClN4OS
378.919
WYTJVUVCSUWZTH-UHFFFAOYSA-N
ym 298198 hydrochloride,6-amino-n-cyclohexyl-n,3-dimethylthiazolo 3,2-a benzimidazole-2-carboxamide hydrochloride,ym-298198 hydrochloride hplc,thiazolo 3,2-a benzimidazole-2-carboxamide,6-amino-n-cyclohexyl-n,3-dimethyl,11-amino-n-cyclohexyl-n,3-dimethyl-5-thia-2,7-diazatricyclo 6.4.0.0_,? dodeca-1 12 ,3,6,8,10-pentaene-4-carboxamide hydrochloride,6-amino-n-cyclohexyl-n,3-dimethyl 1,3 thiazolo 3,2-a benzimidazole-2-carboxamide-hydrogen chloride 1/1
45073464
7-amino-N-cyclohexyl-N,1-dimethyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride
CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4.Cl
This item is not returnable. View return policy
1216398-09-2
C18H23ClN4OS
378.919
WYTJVUVCSUWZTH-UHFFFAOYSA-N
ym 298198 hydrochloride,6-amino-n-cyclohexyl-n,3-dimethylthiazolo 3,2-a benzimidazole-2-carboxamide hydrochloride,ym-298198 hydrochloride hplc,thiazolo 3,2-a benzimidazole-2-carboxamide,6-amino-n-cyclohexyl-n,3-dimethyl,11-amino-n-cyclohexyl-n,3-dimethyl-5-thia-2,7-diazatricyclo 6.4.0.0_,? dodeca-1 12 ,3,6,8,10-pentaene-4-carboxamide hydrochloride,6-amino-n-cyclohexyl-n,3-dimethyl 1,3 thiazolo 3,2-a benzimidazole-2-carboxamide-hydrogen chloride 1/1
45073464
7-amino-N-cyclohexyl-N,1-dimethyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide;hydrochloride
CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4.Cl

Highly potent, selective non-competitive mGlu1 antagonist

Non-competitive antagonist with high affinity and selectivity for mGlu 1 receptors (K i = 19 nM); inactive at other mGlu receptor subtypes (mGlu 2-7 ), ionotropic receptors and glutamate transporters (IC 50 > 10 μM). Inhibits glutamate-induced IP production more potently than CPCCOEt (IC 50 values are 16 nM and 6.3 μM respectively), and is orally active in vivo, demonstrating an antinociceptive effect in hyperalgesic mice. Desmethyl Derivative also available.
Quantity 50mg
Formula Weight 378.92
Percent Purity >99%
Chemical Name or Material YM 298198 hydrochloride

Recommended Storage : Desiccate at +4°C