YPEL3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 154031AP
15403-1-AP was raised against full length of YPEL3 protein (1-119 aa); it can recognize YPEL1-4.YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Protein yippee like 3, yippee like 3 (Drosophila), YPEL3|
|293491, 66090, 83719|
|YPEL3 Fusion Protein Ag7626|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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