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YTHDF2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 267711AP

Catalog No. 50-114-2778


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Description

Description

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5 ft.-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.
Specifications

Specifications

YTHDF2
0.2 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q91YT7, Q9Y5A9
CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2
Rabbit
IgG
150 μL
-20°C
Primary
213541, 51441
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
YTHDF2
Liquid
YTHDF2
YTHDF2 Fusion Protein Ag25348
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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