Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MP Biomedicals™ Z-Val-Ala-Asp-Fluoromethylketone, MP Biomedicals™

Irreversibly inhibits activity of Caspase-1. Z-Val-Ala-Asp-Fluoromethylketone, MP Biomedicals is a cell-permeable pan-caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases. It provides enhanced stability and can be used dire

Specifications

For Use With (Application) Z-Val-Ala-Asp-FMK is non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, (P Kharaziha,2012) which can be used directly with purified enzymes.
Molecular Weight 453.46
Storage Requirements −20°C
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MP03FK10901 View Documents MP Biomedicals™
03FK10901
1mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MP03FK10903 View Documents MP Biomedicals™
03FK10903
3mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MP03FK10905 View Documents MP Biomedicals™
03FK10905
5mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Z-Val-Ala-Asp-FMK is a non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases,(P Kharaziha,2012). The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Z-VAD-FMK is used in apoptosis studies and also in inflammasome studies. It is a potent inhibitor of caspase-1 activation in NLRP3-induced cells.

Specifications

Specifications

Z-Val-Ala-Asp-FMK is non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, (P Kharaziha,2012) which can be used directly with purified enzymes.
453.46
−20°C
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit