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ZAK Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549885

Catalog No. PA549885


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Description

Description

The antibody detects endogenous levels of total ZAK protein.

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications

Specifications

ZAK
Polyclonal
Unconjugated
MAP3K20
Liquid
MAP3K20
Synthesized peptide derived from C-terminal of human MLTK.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9NYL2, Q9ESL4
MLTK
Rabbit
IgG
100 μL
-20°C
Primary
51776, 65964
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