Invitrogen™ ZBTB8A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116783

Catalog No. PIPA5116783

Description

Positive Samples: U-87MG, PC-3, HeLa, Mouse lung, Mouse brain, Rat heart Immunogen sequence: HEPRKESIKK TKHLRLSQPS EVTHYKSSKR EVRTSDSSSH VSQSEEQAQI DAEMDSTPVG YQYGQGSDVT SKSFPDDLPR MRFKCPYCTH VVKRKADLKR HLRCHTGERP YPCQACGKRF SRLDHLSSHF RTIHQACKLI CRKCKRHVTD LTGQVVQEGT RRYRLCNECL AEFGIDSLPI DLEAEQHLMS PSDGDKDSRW H.

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.

Specifications

• Antigen: ZBTB8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZBTB8A
• Gene Alias: 2410081M15Rik; AI480941; BOZF1; BOZ-F1; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; ZBTB8; Zbtb8a; zinc finger and BTB domain containing 8; zinc finger and BTB domain containing 8a; zinc finger and BTB domain-containing protein 8A; ZNF916A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 313049, 653121, 73680
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: B1WBU4, Q96BR9, Q9CWH1
• Gene Symbols: ZBTB8A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human ZBTB8A (NP_001035531).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov