ZC3H8 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA548207

Catalog No. PA548207

Description

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5′-AGGTCTC-3′ sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Specifications

• Antigen: ZC3H8
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q8N5P1, Q9JJ48
• Gene Symbols: ZC3H8
• Immunogen: KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ZC3H8.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Gene: ZC3H8
• Gene Alias: Zinc finger CCCH domain-containing protein 8, ZC3H8, ZC3HDC8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57432, 84524
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid