ZC3H8 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA548207
DescriptionActs as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5 ft.-AGGTCTC-3 ft. sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
|PBS with 0.09% sodium azide|
|Zinc finger CCCH domain-containing protein 8, ZC3H8, ZC3HDC8|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ZC3H8.|
|Antigen affinity chromatography|
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