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ZC3H8 Mouse anti-Human, Clone: OTI4H5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526969

Catalog No. PIMA526969



Description

Description

Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5 ft.-AGGTCTC-3 ft. sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Specifications

Specifications

ZC3H8
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N5P1
Fliz1, ZC3HDC8, zinc finger CCCH domain-containing protein 8, zinc finger CCCH type domain containing 8, zinc finger CCCH-type domain containing 8
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
84524
Immunohistochemistry (Paraffin)
OTI4H5
Unconjugated
ZC3H8
Liquid
ZC3H8
Full length human recombit protein of ZC3H8 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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