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ZCCHC9 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551178

Catalog No. PA551178


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Description

Description

The antibody detects endogenous levels of total ZCCHC9 protein.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC9 (zinc finger, CCHC domain containing 9) is a 271 amino acid protein that contains four CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC9 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Specifications

Specifications

ZCCHC9
Polyclonal
Unconjugated
ZCCHC9
Liquid
ZCCHC9
Fusion protein of human ZCCHC9
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.4 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q8N567
PPP1R41
Rabbit
IgG
100 μL
-20°C
Primary
84240
Documents
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