Invitrogen™ ZDHHC16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577176

Catalog No. PIPA577176

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and contains one DHHC-type zinc finger. Existing as multiple alternatively spliced isoforms, ZDHHC16 interacts with c-Abl and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Via its association with c-Abl, ZDHHC16 may be involved in the regulation of apoptosis. The gene encoding ZDHHC16 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Specifications

• Antigen: ZDHHC16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZDHHC16
• Gene Alias: 1500015N03Rik; Abl-philin 2; ablphilin-2; Aph2; DHHC-16; membrane-associated DHHC16 zinc finger protein; Palmitoyltransferase ZDHHC16; probable palmitoyltransferase ZDHHC16; UNQ2570/PRO6258; Zdhhc16; Zinc finger DHHC domain-containing protein 16; zinc finger DHHC-type containing 16; zinc finger, DHHC domain containing 16; zinc finger, DHHC-type containing 16
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 654495, 74168, 84287
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q969W1, Q9ESG8
• Gene Symbols: ZDHHC16
• Immunogen: Recombinant full length Human ZDHHC16.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG